Sustanon®-250 contains 4 different testosterone esters, each with a different duration of action. These esters are hydrolyzed to testosterone as soon as they enter the general circulation.
Cmax of testosterone in blood plasma is 70 nmol / L and is reached within 24-48 hours after injection of a single dose.
Testosterone concentration returns to baseline 21 days after drug administration.
In blood plasma, testosterone is approximately 98% bound to a specific fraction of globulins that bind testosterone and estradiol.
Testosterone is naturally transformed in the liver to DHT and estriol.
It is excreted mainly by the kidneys (up to 90%) in the form of conjugates of etiocholanolone and androsterone. About 6% of the administered dose is excreted in the bile through the intestines in an unbound form.